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Design and synthesis of new templates derived from pyrrolopyrimidine as selective multidrug-resistance-associated protein inhibitors in multidrug resistance.
Wang S, Wan NC, Harrison J, Miller W, Chuckowree I, Sohal S, Hancox TC, Baker S, Folkes A, Wilson F, Thompson D, Cocks S, Farmer H, Boyce A, Freathy C, Broadbridge J, Scott J, Depledge P, Faint R, Mistry P, Charlton P. Wang S, et al. Among authors: scott j. J Med Chem. 2004 Mar 11;47(6):1339-50. doi: 10.1021/jm0310129. J Med Chem. 2004. PMID: 14998324
Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.
Zindell R, Walker ER, Scott J, Amouzegh P, Wu L, Ermann M, Thomson D, Fisher MB, Fullenwider CL, Grbic H, Kaplita P, Linehan B, Patel M, Patel M, Löbbe S, Block S, Albrecht C, Gemkow MJ, Shih DT, Riether D. Zindell R, et al. Among authors: scott j. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4276-80. doi: 10.1016/j.bmcl.2011.05.068. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21689933
An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction.
East SP, Bamford S, Dietz MG, Eickmeier C, Flegg A, Ferger B, Gemkow MJ, Heilker R, Hengerer B, Kotey A, Loke P, Schänzle G, Schubert HD, Scott J, Whittaker M, Williams M, Zawadzki P, Gerlach K. East SP, et al. Among authors: scott j. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4901-5. doi: 10.1016/j.bmcl.2010.06.078. Epub 2010 Jun 25. Bioorg Med Chem Lett. 2010. PMID: 20638279
Interventions for postburn pruritus.
Sinha S, Gabriel VA, Arora RK, Shin W, Scott J, Bharadia SK, Verly M, Rahmani WM, Nickerson DA, Fraulin FO, Chatterjee P, Ahuja RB, Biernaskie JA. Sinha S, et al. Among authors: scott j. Cochrane Database Syst Rev. 2024 Jun 5;6(6):CD013468. doi: 10.1002/14651858.CD013468.pub2. Cochrane Database Syst Rev. 2024. PMID: 38837237 Review.
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