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A novel peroxisome proliferator-activated receptor alpha/gamma dual agonist demonstrates favorable effects on lipid homeostasis.
Guo Q, Sahoo SP, Wang PR, Milot DP, Ippolito MC, Wu MS, Baffic J, Biswas C, Hernandez M, Lam MH, Sharma N, Han W, Kelly LJ, MacNaul KL, Zhou G, Desai R, Heck JV, Doebber TW, Berger JP, Moller DE, Sparrow CP, Chao YS, Wright SD. Guo Q, et al. Among authors: hernandez m. Endocrinology. 2004 Apr;145(4):1640-8. doi: 10.1210/en.2003-1270. Epub 2003 Dec 30. Endocrinology. 2004. PMID: 14701675
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.
Singh SB, Ondeyka JG, Liu W, Chen S, Chen TS, Li X, Bouffard A, Dropinski J, Jones AB, McCormick S, Hayes N, Wang J, Sharma N, Macnaul K, Hernandez M, Chao YS, Baffic J, Lam MH, Burton C, Sparrow CP, Menke JG. Singh SB, et al. Among authors: hernandez m. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2824-8. doi: 10.1016/j.bmcl.2005.03.100. Bioorg Med Chem Lett. 2005. PMID: 15911262
Regulation of the angiopoietin-like protein 3 gene by LXR.
Kaplan R, Zhang T, Hernandez M, Gan FX, Wright SD, Waters MG, Cai TQ. Kaplan R, et al. Among authors: hernandez m. J Lipid Res. 2003 Jan;44(1):136-43. doi: 10.1194/jlr.m200367-jlr200. J Lipid Res. 2003. PMID: 12518032 Free article.
Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.
Liu W, Chen S, Dropinski J, Colwell L, Robins M, Szymonifka M, Hayes N, Sharma N, MacNaul K, Hernandez M, Burton C, Sparrow CP, Menke JG, Singh SB. Liu W, et al. Among authors: hernandez m. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4574-8. doi: 10.1016/j.bmcl.2005.06.100. Bioorg Med Chem Lett. 2005. PMID: 16125384
4,632 results