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Pyrrolidine-5,5-trans-lactams. 5. Pharmacokinetic optimization of inhibitors of hepatitis C virus NS3/4A protease.
Org Lett. 2003 Nov 27;5(24):4631-4. doi: 10.1021/ol035827n.
Org Lett. 2003.
PMID: 14627401
Pyrrolidine-5,5-trans-lactams. 1. Synthesis and incorporation into inhibitors of hepatitis C virus NS3/4A protease.
Andrews DM, Carey SJ, Chaignot H, Coomber BA, Gray NM, Hind SL, Jones PS, Mills G, Robinson JE, Slater MJ.
Andrews DM, et al. Among authors: hind sl.
Org Lett. 2002 Dec 12;4(25):4475-8. doi: 10.1021/ol027013x.
Org Lett. 2002.
PMID: 12465916
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Pyrrolidine-5,5-trans-lactams. 2. The use of X-ray crystal structure data in the optimization of P3 and P4 substituents.
Andrews DM, Chaignot H, Coomber BA, Good AC, Hind SL, Johnson MR, Jones PS, Mills G, Robinson JE, Skarzynski T, Slater MJ, Somers DO.
Andrews DM, et al. Among authors: hind sl.
Org Lett. 2002 Dec 12;4(25):4479-82. doi: 10.1021/ol027014p.
Org Lett. 2002.
PMID: 12465917
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Design and synthesis of spiro-cyclopentenyl and spiro-[1,3]-dithiolanyl substituted pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease.
Andrews DM, Jones PS, Mills G, Hind SL, Slater MJ, Trivedi N, Wareing KJ.
Andrews DM, et al. Among authors: hind sl.
Bioorg Med Chem Lett. 2003 May 19;13(10):1657-60. doi: 10.1016/s0960-894x(03)00274-9.
Bioorg Med Chem Lett. 2003.
PMID: 12729635
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The design of potent, non-peptidic inhibitors of hepatitis C protease.
Andrews DM, Chaignot HM, Coomber BA, Dowle MD, Hind SL, Johnson MR, Jones PS, Mills G, Patikis A, Pateman TJ, Robinson JE, Slater MJ, Trivedi N.
Andrews DM, et al. Among authors: hind sl.
Eur J Med Chem. 2003 Apr;38(4):339-43. doi: 10.1016/s0223-5234(03)00050-3.
Eur J Med Chem. 2003.
PMID: 12750019
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Synthesis and SAR of 4-aryl-2-hydroxy-4-oxobut-2-enoic acids and esters and 2-amino-4-aryl-4-oxobut-2-enoic acids and esters: potent inhibitors of kynurenine-3-hydroxylase as potential neuroprotective agents.
Drysdale MJ, Hind SL, Jansen M, Reinhard JF Jr.
Drysdale MJ, et al. Among authors: hind sl.
J Med Chem. 2000 Jan 13;43(1):123-7. doi: 10.1021/jm990396t.
J Med Chem. 2000.
PMID: 10633043
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Synthesis of unprotected and borane-protected cyclic phosphines using Ru- and Mo- based olefin metathesis catalysts.
Slinn CA, Redgrave AJ, Hind SL, Edlin C, Nolan SP, Gouverneur V.
Slinn CA, et al. Among authors: hind sl.
Org Biomol Chem. 2003 Nov 7;1(21):3820-5. doi: 10.1039/b306940k.
Org Biomol Chem. 2003.
PMID: 14649914
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