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A transient tobacco expression system coupled to MALDI-TOF-MS allows validation of the impact of differential targeting on structure and activity of a recombinant therapeutic glycoprotein produced in plants.
Mokrzycki-Issartel N, Bouchon B, Farrer S, Berland P, Laparra H, Madelmont JC, Theisen M. Mokrzycki-Issartel N, et al. Among authors: bouchon b. FEBS Lett. 2003 Sep 25;552(2-3):170-6. doi: 10.1016/s0014-5793(03)00916-5. FEBS Lett. 2003. PMID: 14527682 Free article.
Proteomic studies of B16 lines: involvement of annexin A1 in melanoma dissemination.
Rondepierre F, Bouchon B, Papon J, Bonnet-Duquennoy M, Kintossou R, Moins N, Maublant J, Madelmont JC, D'Incan M, Degoul F. Rondepierre F, et al. Among authors: bouchon b. Biochim Biophys Acta. 2009 Jan;1794(1):61-9. doi: 10.1016/j.bbapap.2008.09.014. Epub 2008 Oct 8. Biochim Biophys Acta. 2009. PMID: 18952200
N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.
Borel M, Degoul F, Communal Y, Mounetou E, Bouchon B, C-Gaudreault R, Madelmont JC, Miot-Noirault E. Borel M, et al. Among authors: bouchon b. Br J Cancer. 2007 Jun 4;96(11):1684-91. doi: 10.1038/sj.bjc.6603778. Epub 2007 May 8. Br J Cancer. 2007. PMID: 17486131 Free PMC article.
Alkylation of beta-tubulin on Glu 198 by a microtubule disrupter.
Bouchon B, Chambon C, Mounetou E, Papon J, Miot-Noirault E, Gaudreault RC, Madelmont JC, Degoul F. Bouchon B, et al. Mol Pharmacol. 2005 Nov;68(5):1415-22. doi: 10.1124/mol.105.015586. Epub 2005 Aug 12. Mol Pharmacol. 2005. PMID: 16099845
Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.
Trzeciakiewicz A, Fortin S, Moreau E, C-Gaudreault R, Lacroix J, Chambon C, Communal Y, Chezal JM, Miot-Noirault E, Bouchon B, Degoul F. Trzeciakiewicz A, et al. Among authors: bouchon b. Biochem Pharmacol. 2011 May 1;81(9):1116-23. doi: 10.1016/j.bcp.2011.02.014. Epub 2011 Mar 1. Biochem Pharmacol. 2011. PMID: 21371445 Free article.
Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models.
Rondon A, Ty N, Bequignat JB, Quintana M, Briat A, Witkowski T, Bouchon B, Boucheix C, Miot-Noirault E, Pouget JP, Chezal JM, Navarro-Teulon I, Moreau E, Degoul F. Rondon A, et al. Among authors: bouchon b. Sci Rep. 2017 Nov 2;7(1):14918. doi: 10.1038/s41598-017-15051-y. Sci Rep. 2017. PMID: 29097747 Free PMC article.
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