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Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and Egr-1-dependent and mediated via the ATII type 1 but not type 2 receptor. Induction by ATII antagonized by nitric oxide.
Day FL, Rafty LA, Chesterman CN, Khachigian LM. Day FL, et al. Among authors: khachigian lm. J Biol Chem. 1999 Aug 20;274(34):23726-33. doi: 10.1074/jbc.274.34.23726. J Biol Chem. 1999. PMID: 10446131 Free article.
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