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SYNTHESIS OF INDOMETHACIN METABOLITES.
STRACHAN RG, MEISINGER MA, RUYLE WV, HIRSCHMANN R, SHEN TY. STRACHAN RG, et al. Among authors: ruyle wv. J Med Chem. 1964 Nov;7:799-800. doi: 10.1021/jm00336a026. J Med Chem. 1964. PMID: 14262813 No abstract available.
Novel analgesic-antiinflammatory salicylates.
Hannah J, Ruyle WV, Jones H, Matzuk AR, Kelly KW, Witzel BE, Holtz WJ, Houser RA, Shen TY, Sarett LH. Hannah J, et al. Among authors: ruyle wv. J Med Chem. 1978 Nov;21(11):1093-100. doi: 10.1021/jm00209a001. J Med Chem. 1978. PMID: 309947
Discovery of diflunisal.
Hannah J, Ruyle WV, Jones H, Matzuk AR, Kelly KW, Witzel BE, Holtz WJ, Houser RW, Shen TY, Sarett LH. Hannah J, et al. Among authors: ruyle wv. Br J Clin Pharmacol. 1977 Feb;4 Suppl 1(Suppl 1):7S-13S. doi: 10.1111/j.1365-2125.1977.tb04508.x. Br J Clin Pharmacol. 1977. PMID: 328036 Free PMC article.
A new class of angiotensin-converting enzyme inhibitors.
Patchett AA, Harris E, Tristram EW, Wyvratt MJ, Wu MT, Taub D, Peterson ER, Ikeler TJ, ten Broeke J, Payne LG, Ondeyka DL, Thorsett ED, Greenlee WJ, Lohr NS, Hoffsommer RD, Joshua H, Ruyle WV, Rothrock JW, Aster SD, Maycock AL, Robinson FM, Hirschmann R, Sweet CS, Ulm EH, Gross DM, Vassil TC, Stone CA. Patchett AA, et al. Among authors: ruyle wv. Nature. 1980 Nov 20;288(5788):280-3. doi: 10.1038/288280a0. Nature. 1980. PMID: 6253826
Anticoccidial 1-substituted 4(1H)-pyridinone hydrazones.
Douglas AW, Fisher MH, Fishinger JJ, Gund P, Harris EE, Olson G, Patchett AA, Ruyle WV. Douglas AW, et al. Among authors: ruyle wv. J Med Chem. 1977 Jul;20(7):939-43. doi: 10.1021/jm00217a015. J Med Chem. 1977. PMID: 874968
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