Mimoto T - Search Results

1

Kynostatin (KNI)-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine.

Mimoto T, Imai J, Kisanuki S, Enomoto H, Hattori N, Akaji K, Kiso Y. Mimoto T, et al. Chem Pharm Bull (Tokyo). 1992 Aug;40(8):2251-3. doi: 10.1248/cpb.40.2251. Chem Pharm Bull (Tokyo). 1992. PMID: 1423795

2

A synthetic method suitable for the rapid preparation of 13N-labeled dermorphin analogue, H-Tyr-D-Met(O)-Phe-Gly-NH2 (SD-62).

Kiso Y, Iinuma S, Mimoto T, Saji H, Yokoyama A, Akaji K. Kiso Y, et al. Among authors: mimoto t. Chem Pharm Bull (Tokyo). 1991 Oct;39(10):2734-6. doi: 10.1248/cpb.39.2734. Chem Pharm Bull (Tokyo). 1991. PMID: 1687212

3

KNI-102, a novel tripeptide HIV protease inhibitor containing allophenylnorstatine as a transition-state mimic.

Mimoto T, Imai J, Tanaka S, Hattori N, Kisanuki S, Akaji K, Kiso Y. Mimoto T, et al. Chem Pharm Bull (Tokyo). 1991 Nov;39(11):3088-90. doi: 10.1248/cpb.39.3088. Chem Pharm Bull (Tokyo). 1991. PMID: 1799953

4

Rational design and synthesis of a novel class of active site-targeted HIV protease inhibitors containing a hydroxymethylcarbonyl isostere. Use of phenylnorstatine or allophenylnorstatine as a transition-state mimic.

Mimoto T, Imai J, Tanaka S, Hattori N, Takahashi O, Kisanuki S, Nagano Y, Shintani M, Hayashi H, Sakikawa H, et al. Mimoto T, et al. Chem Pharm Bull (Tokyo). 1991 Sep;39(9):2465-7. doi: 10.1248/cpb.39.2465. Chem Pharm Bull (Tokyo). 1991. PMID: 1804562

5

Comparison of a new orally potent tripeptide HIV-1 protease inhibitor (anti-AIDS drug) based on pharmacokinetic characteristics in rats after intravenous and intraduodenal administrations.

Kiriyama A, Mimoto T, Kisanuki S, Kiso Y, Takada K. Kiriyama A, et al. Among authors: mimoto t. Biopharm Drug Dispos. 1993 Nov;14(8):697-707. doi: 10.1002/bdd.2510140806. Biopharm Drug Dispos. 1993. PMID: 8305629

6

Pharmacokinetic study of a tripeptide HIV-1 protease inhibitor, KNI-174, in rats after intravenous and intraduodenal administrations.

Kiriyama A, Mimoto T, Kiso Y, Takada K. Kiriyama A, et al. Among authors: mimoto t. Biopharm Drug Dispos. 1993 Apr;14(3):199-207. doi: 10.1002/bdd.2510140303. Biopharm Drug Dispos. 1993. PMID: 8490108

7

Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere.

Mimoto T, Hattori N, Takaku H, Kisanuki S, Fukazawa T, Terashima K, Kato R, Nojima S, Misawa S, Ueno T, Imai J, Enomoto H, Tanaka S, Sakikawa H, Shintani M, Hayashi H, Kiso Y. Mimoto T, et al. Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1310-26. doi: 10.1248/cpb.48.1310. Chem Pharm Bull (Tokyo). 2000. PMID: 10993230

8

Synthesis of di- and tripeptide analogues containing alpha-ketoamide as a new core structure for inhibition of HIV-1 protease.

Sheha MM, Mahfouz NM, Hassan HY, Youssef AF, Mimoto T, Kiso Y. Sheha MM, et al. Among authors: mimoto t. Eur J Med Chem. 2000 Oct;35(10):887-94. doi: 10.1016/s0223-5234(00)00187-2. Eur J Med Chem. 2000. PMID: 11121614

9

Synthesis and biological evaluation of a 13N-labeled opioid peptide.

Saji H, Tsutsumi D, Kiso Y, Iimuma S, Mimoto T, Akaji K, Magata Y, Nakamura H, Kita A, Konishi J, et al. Saji H, et al. Among authors: mimoto t. Int J Rad Appl Instrum B. 1992 May;19(4):455-60. doi: 10.1016/0883-2897(92)90160-z. Int J Rad Appl Instrum B. 1992. PMID: 1526810

10

KNI-577, a potent small-sized HIV protease inhibitor based on the dipeptide containing the hydroxymethylcarbonyl isostere as an ideal transition-state mimic.

Kiso Y, Yamaguchi S, Matsumoto H, Mimoto T, Kato R, Nojima S, Takaku H, Fukazawa T, Kimura T, Akaji K. Kiso Y, et al. Among authors: mimoto t. Arch Pharm (Weinheim). 1998 Mar;331(3):87-9. doi: 10.1002/(sici)1521-4184(199803)331:3<87::aid-ardp87>3.0.co;2-h. Arch Pharm (Weinheim). 1998. PMID: 9557134 No abstract available.

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