Tsutsumi S - Search Results

1

Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH.

Koizumi M, Morita K, Daigo M, Tsutsumi S, Abe K, Obika S, Imanishi T. Koizumi M, et al. Among authors: tsutsumi s. Nucleic Acids Res. 2003 Jun 15;31(12):3267-73. doi: 10.1093/nar/gkg416. Nucleic Acids Res. 2003. PMID: 12799454 Free PMC article.

2

2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug.

Morita K, Hasegawa C, Kaneko M, Tsutsumi S, Sone J, Ishikawa T, Imanishi T, Koizumi M. Morita K, et al. Among authors: tsutsumi s. Bioorg Med Chem Lett. 2002 Jan 7;12(1):73-6. doi: 10.1016/s0960-894x(01)00683-7. Bioorg Med Chem Lett. 2002. PMID: 11738576

3

Synthesis and properties of 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) as effective antisense oligonucleotides.

Morita K, Takagi M, Hasegawa C, Kaneko M, Tsutsumi S, Sone J, Ishikawa T, Imanishi T, Koizumi M. Morita K, et al. Among authors: tsutsumi s. Bioorg Med Chem. 2003 May 15;11(10):2211-26. doi: 10.1016/s0968-0896(03)00115-9. Bioorg Med Chem. 2003. PMID: 12713831

4

Comparison between properties of 2'-O,4'-C-ethylene-bridged nucleic acid (ENA) phosphorothioate oligonucleotides and N3'-P5' thiophosphoramidate oligonucleotides.

Horie M, Morita K, Kawakami J, Ando O, Koizumi M, Tsutsumi S. Horie M, et al. Among authors: tsutsumi s. Nucleosides Nucleotides Nucleic Acids. 2006 Mar;25(3):231-42. doi: 10.1080/15257770500446881. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 16629117

5

Synthesis and properties of ENA oligonucleotides targeted to human telomerase RNA subunit.

Horie M, Morita K, Kawakami J, Tsutsumi S, Ando O, Koizumi M. Horie M, et al. Among authors: tsutsumi s. Nucleic Acids Symp Ser (Oxf). 2005;(49):171-2. doi: 10.1093/nass/49.1.171. Nucleic Acids Symp Ser (Oxf). 2005. PMID: 17150688

6

2'-O,4'-C-ethylene-bridged nucleic acids (ENA) with nuclease-resistance and high affinity for RNA.

Morita K, Hasegawa C, Kaneko M, Tsutsumi S, Sone J, Ishikawa T, Imanishi T, Koizumi M. Morita K, et al. Among authors: tsutsumi s. Nucleic Acids Res Suppl. 2001;(1):241-2. doi: 10.1093/nass/1.1.241. Nucleic Acids Res Suppl. 2001. PMID: 12836354

7

Biologically active oligodeoxyribonucleotides--IX. Synthesis and anti-HIV-1 activity of hexadeoxyribonucleotides, TGGGAG, bearing 3'- and 5'-end-modification.

Koizumi M, Koga R, Hotoda H, Momota K, Ohmine T, Furukawa H, Agatsuma T, Nishigaki T, Abe K, Kosaka T, Tsutsumi S, Sone J, Kaneko M, Kimura S, Shimada K. Koizumi M, et al. Among authors: tsutsumi s. Bioorg Med Chem. 1997 Dec;5(12):2235-43. doi: 10.1016/s0968-0896(97)00161-2. Bioorg Med Chem. 1997. PMID: 9459021

8

Biologically active oligodeoxyribonucleotides. Part 11: The least phosphate-modification of quadruplex-forming hexadeoxyribonucleotide TGGGAG, bearing 3-and 5-end-modification, with anti-HIV-1 activity.

Koizumi M, Koga R, Hotoda H, Ohmine T, Furukawa H, Agatsuma T, Nishigaki T, Abe K, Kosaka T, Tsutsumi S, Sone J, Kaneko M, Kimura S, Shimada K. Koizumi M, et al. Among authors: tsutsumi s. Bioorg Med Chem. 1998 Dec;6(12):2469-75. doi: 10.1016/s0968-0896(98)80021-7. Bioorg Med Chem. 1998. PMID: 9925303

9

Biologically active oligodeoxyribonucleotides. 10: anti-HIV-1 activity and stability of modified hexanucleotides containing glycerol-skeleton.

Hotoda H, Koizumi M, Ohmine T, Furukawa H, Nishigaki T, Abe K, Kosaka T, Tsutsumi S, Sone J, Kaneko M. Hotoda H, et al. Among authors: tsutsumi s. Nucleosides Nucleotides. 1998 Jan-Mar;17(1-3):243-52. doi: 10.1080/07328319808005173. Nucleosides Nucleotides. 1998. PMID: 9708349

10

Biologically active oligodeoxyribonucleotides. Part 12: N2-methylation of 2'-deoxyguanosines enhances stability of parallel G-quadruplex and anti-HIV-1 activity.

Koizumi M, Akahori K, Ohmine T, Tsutsumi S, Sone J, Kosaka T, Kaneko M, Kimura S, Shimada K. Koizumi M, et al. Among authors: tsutsumi s. Bioorg Med Chem Lett. 2000 Oct 2;10(19):2213-6. doi: 10.1016/s0960-894x(00)00432-7. Bioorg Med Chem Lett. 2000. PMID: 11012032

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