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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, Baker C, Kuruc JD, Gay CL, James LI, Wu G, Zuck P, Rioja I, Furze RC, Prinjha RK, Howell BJ, Swanstrom R, Browne EP, Strahl BD, Dunham RM, Archin NM, Margolis DM. Falcinelli SD, et al. Among authors: ghofrani s. J Clin Invest. 2022 Apr 15;132(8):e157281. doi: 10.1172/JCI157281. J Clin Invest. 2022. PMID: 35426377 Free PMC article.
Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial.
Behr J, Prasse A, Kreuter M, Johow J, Rabe KF, Bonella F, Bonnet R, Grohe C, Held M, Wilkens H, Hammerl P, Koschel D, Blaas S, Wirtz H, Ficker JH, Neumeister W, Schönfeld N, Claussen M, Kneidinger N, Frankenberger M, Hummler S, Kahn N, Tello S, Freise J, Welte T, Neuser P, Günther A; RELIEF investigators. Behr J, et al. Lancet Respir Med. 2021 May;9(5):476-486. doi: 10.1016/S2213-2600(20)30554-3. Epub 2021 Mar 30. Lancet Respir Med. 2021. PMID: 33798455 Clinical Trial.
Defining stable reference genes in HIV latency reversal experiments.
Ceriani C, Streeter GS, Lemu KJ, James KS, Ghofrani S, Allard B, Shook-Sa BE, Margolis DM, Archin NM. Ceriani C, et al. Among authors: ghofrani s. J Virol. 2021 May 10;95(11):e02305-20. doi: 10.1128/JVI.02305-20. Epub 2021 Mar 24. J Virol. 2021. PMID: 33762410 Free PMC article.
Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral Therapy.
Falcinelli SD, Kilpatrick KW, Read J, Murtagh R, Allard B, Ghofrani S, Kirchherr J, James KS, Stuelke E, Baker C, Kuruc JD, Eron JJ, Hudgens MG, Gay CL, Margolis DM, Archin NM. Falcinelli SD, et al. Among authors: ghofrani s. J Infect Dis. 2021 Jul 2;224(1):92-100. doi: 10.1093/infdis/jiaa718. J Infect Dis. 2021. PMID: 33216132 Free PMC article.
Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy.
Falcinelli SD, Shook-Sa BE, Dewey MG, Sridhar S, Read J, Kirchherr J, James KS, Allard B, Ghofrani S, Stuelke E, Baker C, Roan NR, Eron JJ, Kuruc JD, Ramirez C, Gay C, Mollan KR, Margolis DM, Adimora AA, Archin NM. Falcinelli SD, et al. Among authors: ghofrani s. J Infect Dis. 2020 Nov 9;222(11):1843-1852. doi: 10.1093/infdis/jiaa298. J Infect Dis. 2020. PMID: 32496542 Free PMC article.
16 results