Mitchell LG - Search Results

1

Development of spliceosome-mediated RNA trans-splicing (SMaRT) for the correction of inherited skin diseases.

Dallinger G, Puttaraju M, Mitchell LG, Yancey KB, Yee C, Klausegger A, Hintner H, Bauer JW. Dallinger G, et al. Among authors: mitchell lg. Exp Dermatol. 2003 Feb;12(1):37-46. doi: 10.1034/j.1600-0625.2003.120105.x. Exp Dermatol. 2003. PMID: 12631245

2

5' trans-splicing repair of the PLEC1 gene.

Wally V, Klausegger A, Koller U, Lochmüller H, Krause S, Wiche G, Mitchell LG, Hintner H, Bauer JW. Wally V, et al. Among authors: mitchell lg. J Invest Dermatol. 2008 Mar;128(3):568-74. doi: 10.1038/sj.jid.5701152. Epub 2007 Nov 8. J Invest Dermatol. 2008. PMID: 17989727 Free article.

3

5' exon replacement and repair by spliceosome-mediated RNA trans-splicing.

Mansfield SG, Clark RH, Puttaraju M, Kole J, Cohn JA, Mitchell LG, Garcia-Blanco MA. Mansfield SG, et al. Among authors: mitchell lg. RNA. 2003 Oct;9(10):1290-7. doi: 10.1261/rna.5101903. RNA. 2003. PMID: 13130143 Free PMC article.

4

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy.

Puttaraju M, Jamison SF, Mansfield SG, Garcia-Blanco MA, Mitchell LG. Puttaraju M, et al. Among authors: mitchell lg. Nat Biotechnol. 1999 Mar;17(3):246-52. doi: 10.1038/6986. Nat Biotechnol. 1999. PMID: 10096291

5

Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing.

Puttaraju M, DiPasquale J, Baker CC, Mitchell LG, Garcia-Blanco MA. Puttaraju M, et al. Among authors: mitchell lg. Mol Ther. 2001 Aug;4(2):105-14. doi: 10.1006/mthe.2001.0426. Mol Ther. 2001. PMID: 11482981 Free article.

6

A novel screening system improves genetic correction by internal exon replacement.

Koller U, Wally V, Mitchell LG, Klausegger A, Murauer EM, Mayr E, Gruber C, Hainzl S, Hintner H, Bauer JW. Koller U, et al. Among authors: mitchell lg. Nucleic Acids Res. 2011 Sep 1;39(16):e108. doi: 10.1093/nar/gkr465. Epub 2011 Jun 17. Nucleic Acids Res. 2011. PMID: 21685452 Free PMC article.

7

Repair of CFTR mRNA by spliceosome-mediated RNA trans-splicing.

Mansfield SG, Kole J, Puttaraju M, Yang CC, Garcia-Blanco MA, Cohn JA, Mitchell LG. Mansfield SG, et al. Among authors: mitchell lg. Gene Ther. 2000 Nov;7(22):1885-95. doi: 10.1038/sj.gt.3301307. Gene Ther. 2000. PMID: 11127576

8

Molecular imaging of gene expression in living subjects by spliceosome-mediated RNA trans-splicing.

Bhaumik S, Walls Z, Puttaraju M, Mitchell LG, Gambhir SS. Bhaumik S, et al. Among authors: mitchell lg. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8693-8. doi: 10.1073/pnas.0402772101. Epub 2004 May 25. Proc Natl Acad Sci U S A. 2004. PMID: 15161977 Free PMC article.

9

Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing.

Liu X, Jiang Q, Mansfield SG, Puttaraju M, Zhang Y, Zhou W, Cohn JA, Garcia-Blanco MA, Mitchell LG, Engelhardt JF. Liu X, et al. Among authors: mitchell lg. Nat Biotechnol. 2002 Jan;20(1):47-52. doi: 10.1038/nbt0102-47. Nat Biotechnol. 2002. PMID: 11753361

10

Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing.

Chao H, Mansfield SG, Bartel RC, Hiriyanna S, Mitchell LG, Garcia-Blanco MA, Walsh CE. Chao H, et al. Among authors: mitchell lg. Nat Med. 2003 Aug;9(8):1015-9. doi: 10.1038/nm900. Epub 2003 Jul 6. Nat Med. 2003. PMID: 12847523

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