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Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.
Young BA, Sui X, Kiser TD, Hyun SW, Wang P, Sakarya S, Angelini DJ, Schaphorst KL, Hasday JD, Cross AS, Romer LH, Passaniti A, Goldblum SE. Young BA, et al. Among authors: cross as. Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L63-75. doi: 10.1152/ajplung.00423.2002. Epub 2003 Mar 7. Am J Physiol Lung Cell Mol Physiol. 2003. PMID: 12626337 Free article.
TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.
Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D, Bannerman DD, Vogel SN, Goldblum SE. Gong P, et al. Among authors: cross as. J Biol Chem. 2008 May 9;283(19):13437-49. doi: 10.1074/jbc.M707986200. Epub 2008 Mar 7. J Biol Chem. 2008. PMID: 18326860 Free PMC article.
Mobilization of neutrophil sialidase activity desialylates the pulmonary vascular endothelial surface and increases resting neutrophil adhesion to and migration across the endothelium.
Sakarya S, Rifat S, Zhou J, Bannerman DD, Stamatos NM, Cross AS, Goldblum SE. Sakarya S, et al. Among authors: cross as. Glycobiology. 2004 Jun;14(6):481-94. doi: 10.1093/glycob/cwh065. Epub 2004 Mar 24. Glycobiology. 2004. PMID: 15044387
Moreover, neuraminidase treatment of ECs did not change surface expression of adhesion molecules or release of IL-8 and IL-6. Inhibition of endogenous sialidase by either cross-protective antineuraminidase antibodies (45.5% inhibition) or competitive inhibition with pseudo …
Moreover, neuraminidase treatment of ECs did not change surface expression of adhesion molecules or release of IL-8 and IL-6. Inhibition of …
NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia.
Lee C, Liu A, Miranda-Ribera A, Hyun SW, Lillehoj EP, Cross AS, Passaniti A, Grimm PR, Kim BY, Welling PA, Madri JA, DeLisser HM, Goldblum SE. Lee C, et al. Among authors: cross as. J Biol Chem. 2014 Mar 28;289(13):9121-35. doi: 10.1074/jbc.M114.555888. Epub 2014 Feb 18. J Biol Chem. 2014. PMID: 24550400 Free PMC article.
We recently established endothelial cell (EC) expression of NEU1 sialidase (Cross, A. S., Hyun, S. W., Miranda-Ribera, A., Feng, C., Liu, A., Nguyen, C., Zhang, L., Luzina, I. ...NEU1 overexpression also diminished EC adhesion to the Matrigel substrate and restrained EC mi …
We recently established endothelial cell (EC) expression of NEU1 sialidase (Cross, A. S., Hyun, S. W., Miranda-Ribera, A., Feng, C., …
Recruitment of murine neutrophils in vivo through endogenous sialidase activity.
Cross AS, Sakarya S, Rifat S, Held TK, Drysdale BE, Grange PA, Cassels FJ, Wang LX, Stamatos N, Farese A, Casey D, Powell J, Bhattacharjee AK, Kleinberg M, Goldblum SE. Cross AS, et al. J Biol Chem. 2003 Feb 7;278(6):4112-20. doi: 10.1074/jbc.M207591200. Epub 2002 Nov 22. J Biol Chem. 2003. PMID: 12446694 Free article.
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, Passaniti A, Goldblum SE. Cross AS, et al. J Biol Chem. 2012 May 4;287(19):15966-80. doi: 10.1074/jbc.M112.346817. Epub 2012 Mar 8. J Biol Chem. 2012. PMID: 22403397 Free PMC article.
Human airway epithelia express catalytically active NEU3 sialidase.
Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Sun W, Luzina IG, Webb TJ, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE. Lillehoj EP, et al. Among authors: cross as. Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L876-86. doi: 10.1152/ajplung.00322.2013. Epub 2014 Mar 21. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24658138 Free PMC article.
215 results