Novellino E - Search Results

1

Inherent desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist, (S)-CPW 399, as a possible explanation for its excitotoxic action in cultured cerebellar granule cells.

Sinclair C, Reavy H, Grieve A, Schousboe A, Morelli E, Novellino E, Campiani G, Griffiths R. Sinclair C, et al. Among authors: novellino e. Neurochem Int. 2003 May;42(6):499-510. doi: 10.1016/s0197-0186(02)00141-9. Neurochem Int. 2003. PMID: 12547649

2

1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.

Butini S, Pickering DS, Morelli E, Coccone SS, Trotta F, De Angelis M, Guarino E, Fiorini I, Campiani G, Novellino E, Schousboe A, Christensen JK, Gemma S. Butini S, et al. Among authors: novellino e. J Med Chem. 2008 Oct 23;51(20):6614-8. doi: 10.1021/jm800865a. Epub 2008 Sep 24. J Med Chem. 2008. PMID: 18811139

3

Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.

Butini S, Budriesi R, Hamon M, Morelli E, Gemma S, Brindisi M, Borrelli G, Novellino E, Fiorini I, Ioan P, Chiarini A, Cagnotto A, Mennini T, Fracasso C, Caccia S, Campiani G. Butini S, et al. Among authors: novellino e. J Med Chem. 2009 Nov 12;52(21):6946-50. doi: 10.1021/jm901126m. J Med Chem. 2009. PMID: 19831400

4

Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.

Morelli E, Gemma S, Budriesi R, Campiani G, Novellino E, Fattorusso C, Catalanotti B, Coccone SS, Ros S, Borrelli G, Persico M, Fiorini I, Nacci V, Ioan P, Chiarini A, Hamon M, Cagnotto A, Mennini T, Fracasso C, Colovic M, Caccia S, Butini S. Morelli E, et al. Among authors: novellino e. J Med Chem. 2009 Jun 11;52(11):3548-62. doi: 10.1021/jm900018b. J Med Chem. 2009. PMID: 19425598

5

Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR).

Campiani G, Ramunno A, Fiorini I, Nacci V, Morelli E, Novellino E, Goegan M, Mennini T, Sullivan S, Zisterer DM, Williams CD. Campiani G, et al. Among authors: novellino e. J Med Chem. 2002 Sep 12;45(19):4276-81. doi: 10.1021/jm020849l. J Med Chem. 2002. PMID: 12213069

6

Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.

Venskutonyte R, Butini S, Coccone SS, Gemma S, Brindisi M, Kumar V, Guarino E, Maramai S, Valenti S, Amir A, Valadés EA, Frydenvang K, Kastrup JS, Novellino E, Campiani G, Pickering DS. Venskutonyte R, et al. Among authors: novellino e. J Med Chem. 2011 Jul 14;54(13):4793-805. doi: 10.1021/jm2004078. Epub 2011 Jun 13. J Med Chem. 2011. PMID: 21619066

7

Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases.

Campiani G, Fattorusso C, De Angelis M, Catalanotti B, Butini S, Fattorusso R, Fiorini I, Nacci V, Novellino E. Campiani G, et al. Among authors: novellino e. Curr Pharm Des. 2003;9(8):599-625. doi: 10.2174/1381612033391261. Curr Pharm Des. 2003. PMID: 12570795 Review.

8

Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives.

Campiani G, Ramunno A, Maga G, Nacci V, Fattorusso C, Catalanotti B, Morelli E, Novellino E. Campiani G, et al. Among authors: novellino e. Curr Pharm Des. 2002;8(8):615-57. doi: 10.2174/1381612024607207. Curr Pharm Des. 2002. PMID: 11945162 Review.

9

( S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation.

Brogi S, Brindisi M, Butini S, Kshirsagar GU, Maramai S, Chemi G, Gemma S, Campiani G, Novellino E, Fiorenzani P, Pinassi J, Aloisi AM, Gynther M, Venskutonytė R, Han L, Frydenvang K, Kastrup JS, Pickering DS. Brogi S, et al. Among authors: novellino e. J Med Chem. 2018 Mar 8;61(5):2124-2130. doi: 10.1021/acs.jmedchem.8b00099. Epub 2018 Feb 26. J Med Chem. 2018. PMID: 29451794

10

Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.

Campiani G, Butini S, Trotta F, Fattorusso C, Catalanotti B, Aiello F, Gemma S, Nacci V, Novellino E, Stark JA, Cagnotto A, Fumagalli E, Carnovali F, Cervo L, Mennini T. Campiani G, et al. Among authors: novellino e. J Med Chem. 2003 Aug 28;46(18):3822-39. doi: 10.1021/jm0211220. J Med Chem. 2003. PMID: 12930145

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