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Synthesis, radiolabeling, and preliminary biological evaluation of [3H]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl)-piperazine, a potent antagonist radioligand for the P2X7 receptor.
Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Moorman AR, Di Virgilio F, Cattabriga E, Pancaldi C, Gessi S, Borea PA. Romagnoli R, et al. Among authors: cattabriga e. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5709-12. doi: 10.1016/j.bmcl.2004.07.095. Bioorg Med Chem Lett. 2004. PMID: 15482953
Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, [3H]MRE 2029-F20.
Gessi S, Varani K, Merighi S, Cattabriga E, Pancaldi C, Szabadkai Y, Rizzuto R, Klotz KN, Leung E, Mac Lennan S, Baraldi PG, Borea PA. Gessi S, et al. Among authors: cattabriga e. Mol Pharmacol. 2005 Jun;67(6):2137-47. doi: 10.1124/mol.104.009225. Epub 2005 Mar 23. Mol Pharmacol. 2005. PMID: 15788741
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