Antonello A - Search Results

1

Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure.

Bolognesi ML, Bixel MG, Marucci G, Bartolini M, Krauss M, Angeli P, Antonello A, Rosini M, Tumiatti V, Hucho F, Melchiorre C. Bolognesi ML, et al. Among authors: antonello a. J Med Chem. 2002 Jul 18;45(15):3286-95. doi: 10.1021/jm020835f. J Med Chem. 2002. PMID: 12109912

2

Polymethylene tetraamine backbone as template for the development of biologically active polyamines.

Melchiorre C, Antonello A, Banzi R, Bolognesi ML, Minarini A, Rosini M, Tumiatti V. Melchiorre C, et al. Among authors: antonello a. Med Res Rev. 2003 Mar;23(2):200-33. doi: 10.1002/med.10029. Med Res Rev. 2003. PMID: 12500289 Review.

3

Design, synthesis and biological evaluation of ambenonium derivatives as AChE inhibitors.

Bolognesi ML, Cavalli A, Andrisano V, Bartolini M, Banzi R, Antonello A, Rosini M, Melchiorre C. Bolognesi ML, et al. Among authors: antonello a. Farmaco. 2003 Sep;58(9):917-28. doi: 10.1016/S0014-827X(03)00150-2. Farmaco. 2003. PMID: 13679187

4

Rosini M, Antonello A, Cavalli A, Bolognesi ML, Minarini A, Marucci G, Poggesi E, Leonardi A, Melchiorre C. Rosini M, et al. Among authors: antonello a. J Med Chem. 2003 Nov 6;46(23):4895-903. doi: 10.1021/jm030952q. J Med Chem. 2003. PMID: 14584940

5

Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds.

Antonello A, Hrelia P, Leonardi A, Marucci G, Rosini M, Tarozzi A, Tumiatti V, Melchiorre C. Antonello A, et al. J Med Chem. 2005 Jan 13;48(1):28-31. doi: 10.1021/jm049153d. J Med Chem. 2005. PMID: 15633998

6

Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects.

Antonello A, Tarozzi A, Morroni F, Cavalli A, Rosini M, Hrelia P, Bolognesi ML, Melchiorre C. Antonello A, et al. J Med Chem. 2006 Nov 16;49(23):6642-5. doi: 10.1021/jm0608762. J Med Chem. 2006. PMID: 17154492

7

Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin.

Søhoel H, Liljefors T, Ley SV, Oliver SF, Antonello A, Smith MD, Olsen CE, Isaacs JT, Christensen SB. Søhoel H, et al. Among authors: antonello a. J Med Chem. 2005 Nov 3;48(22):7005-11. doi: 10.1021/jm058036v. J Med Chem. 2005. PMID: 16250659

8

Synthesis of the thapsigargins.

Ley SV, Antonello A, Balskus EP, Booth DT, Christensen SB, Cleator E, Gold H, Högenauer K, Hünger U, Myers RM, Oliver SF, Simic O, Smith MD, Søhoel H, Woolford AJ. Ley SV, et al. Among authors: antonello a. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12073-8. doi: 10.1073/pnas.0403300101. Epub 2004 Jun 28. Proc Natl Acad Sci U S A. 2004. PMID: 15226504 Free PMC article.

9

Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition.

Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Andrews SP, et al. Among authors: antonello a. Chemistry. 2007;13(20):5688-712. doi: 10.1002/chem.200700302. Chemistry. 2007. PMID: 17508363

10

A route to the thapsigargins from (S)-carvone providing a substrate-controlled total synthesis of trilobolide, nortrilobolide, and thapsivillosin F.

Oliver SF, Högenauer K, Simic O, Antonello A, Smith MD, Ley SV. Oliver SF, et al. Among authors: antonello a. Angew Chem Int Ed Engl. 2003 Dec 15;42(48):5996-6000. doi: 10.1002/anie.200353140. Angew Chem Int Ed Engl. 2003. PMID: 14679553 No abstract available.

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