Pivnichny JV - Search Results

1

Rapid pharmacokinetic screening for the selection of new drug discovery candidates using a generic isocratic liquid chromatography--atmospheric pressure ionization tandem mass spectrometry method.

Colwell LF Jr, Tamvakopoulos CS, Wang PR, Pivnichny JV, Shih TL. Colwell LF Jr, et al. Among authors: pivnichny jv. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 May 25;772(1):89-98. doi: 10.1016/s1570-0232(02)00061-2. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12016019

2

Comparison of the effects of perfusion in determining brain penetration (brain-to-plasma ratios) of small molecules in rats.

Fenyk-Melody JE, Shen X, Peng Q, Pikounis W, Colwell L, Pivnichny J, Anderson LC, Tamvakopoulos CS. Fenyk-Melody JE, et al. Comp Med. 2004 Aug;54(4):378-81. Comp Med. 2004. PMID: 15357317

3

Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry.

Tong XS, Wang J, Zheng S, Pivnichny JV, Griffin PR, Shen X, Donnelly M, Vakerich K, Nunes C, Fenyk-Melody J. Tong XS, et al. Among authors: pivnichny jv. Anal Chem. 2002 Dec 15;74(24):6305-13. doi: 10.1021/ac025988p. Anal Chem. 2002. PMID: 12510753

4

High throughput metabolic stability screen for lead optimization in drug discovery.

Tong XS, Xu S, Zheng S, Pivnichny JV, Martin J, Dufresne C. Tong XS, et al. Among authors: pivnichny jv. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Apr 3;833(2):165-73. doi: 10.1016/j.jchromb.2006.01.037. Epub 2006 Feb 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16504609

5

Potent, orally absorbed glucagon receptor antagonists.

de Laszlo SE, Hacker C, Li B, Kim D, MacCoss M, Mantlo N, Pivnichny JV, Colwell L, Koch GE, Cascieri MA, Hagmann WK. de Laszlo SE, et al. Among authors: pivnichny jv. Bioorg Med Chem Lett. 1999 Mar 8;9(5):641-6. doi: 10.1016/s0960-894x(99)00081-5. Bioorg Med Chem Lett. 1999. PMID: 10201821

6

Simple and sensitive liquid chromatography/tandem mass spectrometry method for the determination of diazepam and its major metabolites in rat cerebrospinal fluid.

Wang J, Shen X, Fenyk-Melody J, Pivnichny JV, Tong X. Wang J, et al. Among authors: pivnichny jv. Rapid Commun Mass Spectrom. 2003;17(6):519-25. doi: 10.1002/rcm.942. Rapid Commun Mass Spectrom. 2003. PMID: 12621612

7

Characterization of a technique for rapid pharmacokinetic studies of multiple co-eluting compounds by LC/MS/MS.

Tong X, Ita IE, Wang J, Pivnichny JV. Tong X, et al. Among authors: pivnichny jv. J Pharm Biomed Anal. 1999 Sep;20(5):773-84. doi: 10.1016/s0731-7085(99)00079-5. J Pharm Biomed Anal. 1999. PMID: 10701985

8

Automated sample preparation and purification of homogenized brain tissues.

Xu S, Zheng S, Shen X, Yao Z, Pivnichny J, Tong X. Xu S, et al. J Pharm Biomed Anal. 2007 Jun 28;44(2):581-5. doi: 10.1016/j.jpba.2007.02.033. Epub 2007 Mar 2. J Pharm Biomed Anal. 2007. PMID: 17451908

9

High-throughput pharmacokinetics screen of VLA-4 antagonists by LC/MS/MS coupled with automated solid-phase extraction sample preparation.

Tong XS, Wang J, Zheng S, Pivnichny JV. Tong XS, et al. Among authors: pivnichny jv. J Pharm Biomed Anal. 2004 Jun 29;35(4):867-77. doi: 10.1016/j.jpba.2004.02.017. J Pharm Biomed Anal. 2004. PMID: 15193731

10

Liquid chromatographic determination of ivermectin in animal plasma with trifluoroacetic anhydride and N-methylimidazole as the derivatization reagent.

de Montigny P, Shim JS, Pivnichny JV. de Montigny P, et al. Among authors: pivnichny jv. J Pharm Biomed Anal. 1990;8(6):507-11. doi: 10.1016/0731-7085(90)80060-3. J Pharm Biomed Anal. 1990. PMID: 2093388

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