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Infection of human dendritic cells by a sindbis virus replicon vector is determined by a single amino acid substitution in the E2 glycoprotein.
Gardner JP, Frolov I, Perri S, Ji Y, MacKichan ML, zur Megede J, Chen M, Belli BA, Driver DA, Sherrill S, Greer CE, Otten GR, Barnett SW, Liu MA, Dubensky TW, Polo JM. Gardner JP, et al. Among authors: zur megede j. J Virol. 2000 Dec;74(24):11849-57. doi: 10.1128/jvi.74.24.11849-11857.2000. J Virol. 2000. PMID: 11090185 Free PMC article.
Beta7-integrin-independent enhancement of mucosal and systemic anti-HIV antibody responses following combined mucosal and systemic gene delivery.
Goodsell A, Zhou F, Gupta S, Singh M, Malyala P, Kazzaz J, Greer C, Legg H, Tang T, Zur Megede J, Srivastava R, Barnett SW, Donnelly JJ, Luciw PA, Polo J, O'Hagan DT, Vajdy M. Goodsell A, et al. Among authors: zur megede j. Immunology. 2008 Mar;123(3):378-89. doi: 10.1111/j.1365-2567.2007.02702.x. Epub 2007 Oct 17. Immunology. 2008. PMID: 17944930 Free PMC article.
Long-term protection in hamsters against human parainfluenza virus type 3 following mucosal or combinations of mucosal and systemic immunizations with chimeric alphavirus-based replicon particles.
Greer CE, Zhou F, Goodsell A, Legg HS, Tang Z, zur Megede J, Uematsu Y, Polo JM, Vajdy M. Greer CE, et al. Among authors: zur megede j. Scand J Immunol. 2007 Dec;66(6):645-53. doi: 10.1111/j.1365-3083.2007.02019.x. Epub 2007 Oct 17. Scand J Immunol. 2007. PMID: 17944814 Free article.
Antibody-mediated protection against mucosal simian-human immunodeficiency virus challenge of macaques immunized with alphavirus replicon particles and boosted with trimeric envelope glycoprotein in MF59 adjuvant.
Barnett SW, Burke B, Sun Y, Kan E, Legg H, Lian Y, Bost K, Zhou F, Goodsell A, Zur Megede J, Polo J, Donnelly J, Ulmer J, Otten GR, Miller CJ, Vajdy M, Srivastava IK. Barnett SW, et al. Among authors: zur megede j. J Virol. 2010 Jun;84(12):5975-85. doi: 10.1128/JVI.02533-09. Epub 2010 Apr 14. J Virol. 2010. PMID: 20392857 Free PMC article.
A therapeutic SIV DNA vaccine elicits T-cell immune responses, but no sustained control of viremia in SIVmac239-infected rhesus macaques.
zur Megede J, Sanders-Beer B, Silvera P, Golightly D, Bowlsbey A, Hebblewaite D, Sites D, Nieves-Duran L, Srivastava R, Otten GR, Rabussay D, Zhang L, Ulmer JB, Barnett SW, Donnelly JJ. zur Megede J, et al. AIDS Res Hum Retroviruses. 2008 Aug;24(8):1103-16. doi: 10.1089/aid.2008.0055. AIDS Res Hum Retroviruses. 2008. PMID: 18620495 Free PMC article.
Evaluation of envelope vaccines derived from the South African subtype C human immunodeficiency virus type 1 TV1 strain.
Lian Y, Srivastava I, Gómez-Román VR, Zur Megede J, Sun Y, Kan E, Hilt S, Engelbrecht S, Himathongkham S, Luciw PA, Otten G, Ulmer JB, Donnelly JJ, Rabussay D, Montefiori D, van Rensburg EJ, Barnett SW. Lian Y, et al. Among authors: zur megede j. J Virol. 2005 Nov;79(21):13338-49. doi: 10.1128/JVI.79.21.13338-13349.2005. J Virol. 2005. PMID: 16227256 Free PMC article.
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