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Treatment of Alzheimer's disease with clioquinol.
Regland B, Lehmann W, Abedini I, Blennow K, Jonsson M, Karlsson I, Sjögren M, Wallin A, Xilinas M, Gottfries CG. Regland B, et al. Among authors: xilinas m. Dement Geriatr Cogn Disord. 2001 Nov-Dec;12(6):408-14. doi: 10.1159/000051288. Dement Geriatr Cogn Disord. 2001. PMID: 11598313 Clinical Trial.
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial.
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, Davis S, Beyreuther K, Tanzi RE, Masters CL. Ritchie CW, et al. Among authors: xilinas m. Arch Neurol. 2003 Dec;60(12):1685-91. doi: 10.1001/archneur.60.12.1685. Arch Neurol. 2003. PMID: 14676042 Clinical Trial.
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, Zheng H, Tanzi RE, Masters CL, Bush AI. Cherny RA, et al. Among authors: xilinas me. Neuron. 2001 Jun;30(3):665-76. doi: 10.1016/s0896-6273(01)00317-8. Neuron. 2001. PMID: 11430801 Free article.
Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
White AR, Du T, Laughton KM, Volitakis I, Sharples RA, Xilinas ME, Hoke DE, Holsinger RM, Evin G, Cherny RA, Hill AF, Barnham KJ, Li QX, Bush AI, Masters CL. White AR, et al. Among authors: xilinas me. J Biol Chem. 2006 Jun 30;281(26):17670-80. doi: 10.1074/jbc.M602487200. Epub 2006 Apr 28. J Biol Chem. 2006. PMID: 16648635 Free article.
Rimactan parenteral formulation in clinical use.
Kissling M, Xilinas M. Kissling M, et al. Among authors: xilinas m. J Int Med Res. 1981;9(6):459-9. doi: 10.1177/030006058100900607. J Int Med Res. 1981. PMID: 7319132 No abstract available.
14 results