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Page 1
Identification of selective inhibitors of cyclin dependent kinase 4.
Carini DJ, Kaltenbach RF, Liu J, Benfield PA, Boylan J, Boisclair M, Brizuela L, Burton CR, Cox S, Grafstrom R, Harrison BA, Harrison K, Akamike E, Markwalder JA, Nakano Y, Seitz SP, Sharp DM, Trainor GL, Sielecki TM. Carini DJ, et al. Among authors: boisclair m. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2209-11. doi: 10.1016/s0960-894x(01)00416-4. Bioorg Med Chem Lett. 2001. PMID: 11514172
Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors.
Rossi KA, Markwalder JA, Seitz SP, Chang CH, Cox S, Boisclair MD, Brizuela L, Brenner SL, Stouten PF. Rossi KA, et al. Among authors: boisclair md. J Comput Aided Mol Des. 2005 Feb;19(2):111-22. doi: 10.1007/s10822-005-1778-x. J Comput Aided Mol Des. 2005. PMID: 16075305
Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases.
Markwalder JA, Arnone MR, Benfield PA, Boisclair M, Burton CR, Chang CH, Cox SS, Czerniak PM, Dean CL, Doleniak D, Grafstrom R, Harrison BA, Kaltenbach RF 3rd, Nugiel DA, Rossi KA, Sherk SR, Sisk LM, Stouten P, Trainor GL, Worland P, Seitz SP. Markwalder JA, et al. Among authors: boisclair m. J Med Chem. 2004 Nov 18;47(24):5894-911. doi: 10.1021/jm020455u. J Med Chem. 2004. PMID: 15537345
Indenopyrazoles as novel cyclin dependent kinase (CDK) inhibitors.
Nugiel DA, Etzkorn AM, Vidwans A, Benfield PA, Boisclair M, Burton CR, Cox S, Czerniak PM, Doleniak D, Seitz SP. Nugiel DA, et al. Among authors: boisclair m. J Med Chem. 2001 Apr 26;44(9):1334-6. doi: 10.1021/jm0100032. J Med Chem. 2001. PMID: 11311054 No abstract available.
Quinazolines as cyclin dependent kinase inhibitors.
Sielecki TM, Johnson TL, Liu J, Muckelbauer JK, Grafstrom RH, Cox S, Boylan J, Burton CR, Chen H, Smallwood A, Chang CH, Boisclair M, Benfield PA, Trainor GL, Seitz SP. Sielecki TM, et al. Among authors: boisclair m. Bioorg Med Chem Lett. 2001 May 7;11(9):1157-60. doi: 10.1016/s0960-894x(01)00185-8. Bioorg Med Chem Lett. 2001. PMID: 11354366
Structure-activity relationship studies of flavopiridol analogues.
Murthi KK, Dubay M, McClure C, Brizuela L, Boisclair MD, Worland PJ, Mansuri MM, Pal K. Murthi KK, et al. Among authors: boisclair md. Bioorg Med Chem Lett. 2000 May 15;10(10):1037-41. doi: 10.1016/s0960-894x(00)00156-6. Bioorg Med Chem Lett. 2000. PMID: 10843211
28 results