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Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin.
Maag D, Castro C, Hong Z, Cameron CE. Maag D, et al. Among authors: hong z. J Biol Chem. 2001 Dec 7;276(49):46094-8. doi: 10.1074/jbc.C100349200. Epub 2001 Oct 15. J Biol Chem. 2001. PMID: 11602568 Free article.
Recently, we demonstrated that the antiviral activity of ribavirin can result from the ability of a viral RNA polymerase to utilize ribavirin triphosphate and to incorporate this nucleotide with reduced specificity, thereby mutagenizing the genome and decreasing the yield of infe …
Recently, we demonstrated that the antiviral activity of ribavirin can result from the ability of a viral RNA polymerase to utilize ribaviri …
Mechanisms of action of ribavirin in antiviral therapies.
Tam RC, Lau JY, Hong Z. Tam RC, et al. Among authors: hong z. Antivir Chem Chemother. 2001 Sep;12(5):261-72. doi: 10.1177/095632020101200501. Antivir Chem Chemother. 2001. PMID: 11900345 Free article. Review.
Dinucleotide analogues as novel inhibitors of RNA-dependent RNA polymerase of hepatitis C Virus.
Zhong W, An H, Barawkar D, Hong Z. Zhong W, et al. Among authors: hong z. Antimicrob Agents Chemother. 2003 Aug;47(8):2674-81. doi: 10.1128/AAC.47.8.2674-2681.2003. Antimicrob Agents Chemother. 2003. PMID: 12878540 Free PMC article.
A. Lesburg, D. Maag, S. K. Ghosh, C. E. Cameron, J. Y. Lau, and Z. Hong, J. Virol. 74:9134-9143, 2000). In this study, we further demonstrated that dinucleotide analogues could serve as inhibitors of de novo initiation of RNA synthesis directed by HCV NS5B. ...
A. Lesburg, D. Maag, S. K. Ghosh, C. E. Cameron, J. Y. Lau, and Z. Hong, J. Virol. 74:9134-9143, 2000). In this study, we furt …
2,964 results