Orlean P - Search Results

1

Dolichol phosphate mannose synthase from the filamentous fungus Trichoderma reesei belongs to the human and Schizosaccharomyces pombe class of the enzyme.

Kruszewska JS, Saloheimo M, Migdalski A, Orlean P, Penttilä M, Palamarczyk G. Kruszewska JS, et al. Among authors: orlean p. Glycobiology. 2000 Oct;10(10):983-91. doi: 10.1093/glycob/10.10.983. Glycobiology. 2000. PMID: 11030744

2

Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombe.

Colussi PA, Taron CH, Mack JC, Orlean P. Colussi PA, et al. Among authors: orlean p. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7873-8. doi: 10.1073/pnas.94.15.7873. Proc Natl Acad Sci U S A. 1997. PMID: 9223280 Free PMC article.

3

The Saccharomyces cerevisiae DPM1 gene encoding dolichol-phosphate-mannose synthase is able to complement a glycosylation-defective mammalian cell line.

Beck PJ, Orlean P, Albright C, Robbins PW, Gething MJ, Sambrook JF. Beck PJ, et al. Among authors: orlean p. Mol Cell Biol. 1990 Sep;10(9):4612-22. doi: 10.1128/mcb.10.9.4612-4622.1990. Mol Cell Biol. 1990. PMID: 2201896 Free PMC article.

4

The essential Schizosaccharomyces pombe gpil+ gene complements a bakers' yeast GPI anchoring mutant and is required for efficient cell separation.

Colussi PA, Orlean P. Colussi PA, et al. Among authors: orlean p. Yeast. 1997 Feb;13(2):139-50. doi: 10.1002/(SICI)1097-0061(199702)13:2<139::AID-YEA69>3.0.CO;2-S. Yeast. 1997. PMID: 9046095

5

Cloning and sequencing of the yeast gene for dolichol phosphate mannose synthase, an essential protein.

Orlean P, Albright C, Robbins PW. Orlean P, et al. J Biol Chem. 1988 Nov 25;263(33):17499-507. J Biol Chem. 1988. PMID: 3053713 Free article.

6

The essential Smp3 protein is required for addition of the side-branching fourth mannose during assembly of yeast glycosylphosphatidylinositols.

Grimme SJ, Westfall BA, Wiedman JM, Taron CH, Orlean P. Grimme SJ, et al. Among authors: orlean p. J Biol Chem. 2001 Jul 20;276(29):27731-9. doi: 10.1074/jbc.M101986200. Epub 2001 May 16. J Biol Chem. 2001. PMID: 11356840 Free article.

7

Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene.

Leidich SD, Kostova Z, Latek RR, Costello LC, Drapp DA, Gray W, Fassler JS, Orlean P. Leidich SD, et al. Among authors: orlean p. J Biol Chem. 1995 Jun 2;270(22):13029-35. doi: 10.1074/jbc.270.22.13029. J Biol Chem. 1995. PMID: 7768896 Free article.

The gpi1 mutant, identified in this way, is temperature sensitive for growth and defective in vitro in the synthesis of GlcNAc-phosphatidylinositol, the first intermediate in GPI biosynthesis (Leidich, S. D., Drapp, D. A., and Orlean, P. (1994) J. Biol. Chem. 269, 1 …

The gpi1 mutant, identified in this way, is temperature sensitive for growth and defective in vitro in the synthesis of GlcNAc-phosphatidyli …

8

Enzymes that recognize dolichols participate in three glycosylation pathways and are required for protein secretion.

Orlean P. Orlean P. Biochem Cell Biol. 1992 Jun;70(6):438-47. doi: 10.1139/o92-067. Biochem Cell Biol. 1992. PMID: 1333231 Review.

9

Comparative importance in vivo of conserved glutamate residues in the EX7E motif retaining glycosyltransferase Gpi3p, the UDP-GlcNAc-binding subunit of the first enzyme in glycosylphosphatidylinositol assembly.

Kostova Z, Yan BC, Vainauskas S, Schwartz R, Menon AK, Orlean P. Kostova Z, et al. Among authors: orlean p. Eur J Biochem. 2003 Nov;270(22):4507-14. doi: 10.1046/j.1432-1033.2003.03844.x. Eur J Biochem. 2003. PMID: 14622279 Free article.

10

Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.

Taron CH, Wiedman JM, Grimme SJ, Orlean P. Taron CH, et al. Among authors: orlean p. Mol Biol Cell. 2000 May;11(5):1611-30. doi: 10.1091/mbc.11.5.1611. Mol Biol Cell. 2000. PMID: 10793139 Free PMC article.

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