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The Asp9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis. REGRESS Study Group, Interuniversity Cardiology Institute, Utrecht, The Netherlands. Regression Growth Evaluation Statin Study.
Jukema JW, van Boven AJ, Groenemeijer B, Zwinderman AH, Reiber JH, Bruschke AV, Henneman JA, Molhoek GP, Bruin T, Jansen H, Gagné E, Hayden MR, Kastelein JJ. Jukema JW, et al. Among authors: kastelein jj. Circulation. 1996 Oct 15;94(8):1913-8. doi: 10.1161/01.cir.94.8.1913. Circulation. 1996. PMID: 8873668 Clinical Trial.
Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group.
Groenemeijer BE, Hallman MD, Reymer PW, Gagné E, Kuivenhoven JA, Bruin T, Jansen H, Lie KI, Bruschke AV, Boerwinkle E, Hayden MR, Kastelein JJ. Groenemeijer BE, et al. Among authors: kastelein jj. Circulation. 1997 Jun 17;95(12):2628-35. doi: 10.1161/01.cir.95.12.2628. Circulation. 1997. PMID: 9193431 Clinical Trial.
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects.
Boekholdt SM, Sacks FM, Jukema JW, Shepherd J, Freeman DJ, McMahon AD, Cambien F, Nicaud V, de Grooth GJ, Talmud PJ, Humphries SE, Miller GJ, Eiriksdottir G, Gudnason V, Kauma H, Kakko S, Savolainen MJ, Arca M, Montali A, Liu S, Lanz HJ, Zwinderman AH, Kuivenhoven JA, Kastelein JJ. Boekholdt SM, et al. Among authors: kastelein jj. Circulation. 2005 Jan 25;111(3):278-87. doi: 10.1161/01.CIR.0000153341.46271.40. Epub 2005 Jan 17. Circulation. 2005. PMID: 15655129
Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels.
Boekholdt SM, Souverein OW, Tanck MW, Hovingh GK, Kuivenhoven JA, Peters RI, Jansen H, Schiffers PM, van der Wall EE, Doevendans PA, Reitsma PH, Zwinderman AH, Kastelein JJ, Jukema JW. Boekholdt SM, et al. Among authors: kastelein jj. Clin Genet. 2006 Mar;69(3):263-70. doi: 10.1111/j.1399-0004.2006.00578.x. Clin Genet. 2006. PMID: 16542392
894 results