Hruby VJ - Search Results

1

Conformation-activity relationships of opioid peptides with selective activities at opioid receptors.

Hruby VJ, Agnes RS. Hruby VJ, et al. Biopolymers. 1999;51(6):391-410. doi: 10.1002/(SICI)1097-0282(1999)51:6<391::AID-BIP3>3.0.CO;2-X. Biopolymers. 1999. PMID: 10797229 Review.

2

Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.

Lee YS, Agnes RS, Badghisi H, Davis P, Ma SW, Lai J, Porreca F, Hruby VJ. Lee YS, et al. Among authors: hruby vj. J Med Chem. 2006 Mar 9;49(5):1773-80. doi: 10.1021/jm050851n. J Med Chem. 2006. PMID: 16509592 Free PMC article.

3

Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.

Agnes RS, Lee YS, Davis P, Ma SW, Badghisi H, Porreca F, Lai J, Hruby VJ. Agnes RS, et al. Among authors: hruby vj. J Med Chem. 2006 May 18;49(10):2868-75. doi: 10.1021/jm050921q. J Med Chem. 2006. PMID: 16686530 Free PMC article.

4

New paradigms and tools in drug design for pain and addiction.

Hruby VJ, Porreca F, Yamamura HI, Tollin G, Agnes RS, Lee YS, Cai M, Alves I, Cowell S, Varga E, Davis P, Salamon Z, Roeske W, Vanderah T, Lai J. Hruby VJ, et al. AAPS J. 2006 Jul 14;8(3):E450-60. doi: 10.1208/aapsj080353. AAPS J. 2006. PMID: 17025262 Free PMC article. Review.

5

Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors.

Lee YS, Agnes RS, Davis P, Ma SW, Badghisi H, Lai J, Porreca F, Hruby VJ. Lee YS, et al. Among authors: hruby vj. J Med Chem. 2007 Jan 11;50(1):165-8. doi: 10.1021/jm061268p. J Med Chem. 2007. PMID: 17201419 Free PMC article.

6

Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors.

Lee YS, Nyberg J, Moye S, Agnes RS, Davis P, Ma SW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Lee YS, et al. Among authors: hruby vj. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2161-5. doi: 10.1016/j.bmcl.2007.01.114. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17329100 Free PMC article.

7

Opioid and melanocortin receptors: do they have overlapping pharmacophores?

Lee YS, Agnes RS, Cain JP, Kulkarni V, Cai M, Salibay C, Ciano K, Petrov R, Mayorov A, Vagner J, Trivedi D, Davis P, Ma SW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Lee YS, et al. Among authors: hruby vj. Biopolymers. 2008;90(3):433-8. doi: 10.1002/bip.20814. Biopolymers. 2008. PMID: 17657709 Free PMC article.

8

Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.

Agnes RS, Ying J, Kövér KE, Lee YS, Davis P, Ma SW, Badghisi H, Porreca F, Lai J, Hruby VJ. Agnes RS, et al. Among authors: hruby vj. Peptides. 2008 Aug;29(8):1413-23. doi: 10.1016/j.peptides.2008.03.022. Epub 2008 Apr 10. Peptides. 2008. PMID: 18502541 Free PMC article.

9

Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain.

Hruby VJ, Agnes RS, Davis P, Ma SW, Lee YS, Vanderah TW, Lai J, Porreca F. Hruby VJ, et al. Life Sci. 2003 Jun 27;73(6):699-704. doi: 10.1016/s0024-3205(03)00390-4. Life Sci. 2003. PMID: 12801591 Free PMC article.

10

Novel design of bicyclic beta-turn dipeptides on solid-phase supports and synthesis of [3.3.0]-Bicyclo([2,3])-leu-enkephalin analogues.

Gu X, Ying J, Agnes RS, Navratilova E, Davis P, Stahl G, Porreca F, Yamamura HI, Hruby VJ. Gu X, et al. Among authors: hruby vj. Org Lett. 2004 Sep 16;6(19):3285-8. doi: 10.1021/ol0488183. Org Lett. 2004. PMID: 15355033

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

766 results

Search Page