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Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model: potential application of ribozyme strategy to treat cardiovascular disease.
Yamamoto K, Morishita R, Tomita N, Shimozato T, Nakagami H, Kikuchi A, Aoki M, Higaki J, Kaneda Y, Ogihara T. Yamamoto K, et al. Among authors: shimozato t. Circulation. 2000 Sep 12;102(11):1308-14. doi: 10.1161/01.cir.102.11.1308. Circulation. 2000. PMID: 10982548
Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.
Kanno A, Tanimura N, Ishizaki M, Ohko K, Motoi Y, Onji M, Fukui R, Shimozato T, Yamamoto K, Shibata T, Sano S, Sugahara-Tobinai A, Takai T, Ohto U, Shimizu T, Saitoh S, Miyake K. Kanno A, et al. Among authors: shimozato t. Nat Commun. 2015 Feb 4;6:6119. doi: 10.1038/ncomms7119. Nat Commun. 2015. PMID: 25648980 Free article.
Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist.
Nishi T, Miyazaki S, Takemoto T, Suzuki K, Iio Y, Nakajima K, Ohnuki T, Kawase Y, Nara F, Inaba S, Izumi T, Yuita H, Oshima K, Doi H, Inoue R, Tomisato W, Kagari T, Shimozato T. Nishi T, et al. Among authors: shimozato t. ACS Med Chem Lett. 2011 Mar 2;2(5):368-72. doi: 10.1021/ml100301k. eCollection 2011 May 12. ACS Med Chem Lett. 2011. PMID: 24900318 Free PMC article.
Synthesis and SAR studies of benzyl ether derivatives as potent orally active S1P₁ agonists.
Tsuji T, Suzuki K, Nakamura T, Goto T, Sekiguchi Y, Ikeda T, Fukuda T, Takemoto T, Mizuno Y, Kimura T, Kawase Y, Nara F, Kagari T, Shimozato T, Yahara C, Inaba S, Honda T, Izumi T, Tamura M, Nishi T. Tsuji T, et al. Among authors: shimozato t. Bioorg Med Chem. 2014 Aug 1;22(15):4246-56. doi: 10.1016/j.bmc.2014.05.035. Epub 2014 May 24. Bioorg Med Chem. 2014. PMID: 24909680
Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate.
Ohtoyo M, Machinaga N, Inoue R, Hagihara K, Yuita H, Tamura M, Hashimoto R, Chiba J, Muro F, Watanabe J, Kobayashi Y, Abe K, Kita Y, Nagasaki M, Shimozato T. Ohtoyo M, et al. Among authors: shimozato t. Cell Chem Biol. 2016 May 19;23(5):555-560. doi: 10.1016/j.chembiol.2016.04.007. Epub 2016 May 12. Cell Chem Biol. 2016. PMID: 27185637 Free article.
76 results