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Optimization of dietary folate or low-dose folic acid supplements lower homocysteine but do not enhance endothelial function in healthy adults, irrespective of the methylenetetrahydrofolate reductase (C677T) genotype.
Pullin CH, Ashfield-Watt PA, Burr ML, Clark ZE, Lewis MJ, Moat SJ, Newcombe RG, Powers HJ, Whiting JM, McDowell IF. Pullin CH, et al. Among authors: lewis mj. J Am Coll Cardiol. 2001 Dec;38(7):1799-805. doi: 10.1016/s0735-1097(01)01668-0. J Am Coll Cardiol. 2001. PMID: 11738277 Free article. Clinical Trial.
Reduction in plasma total homocysteine through increasing folate intake in healthy individuals is not associated with changes in measures of antioxidant activity or oxidant damage.
Moat SJ, Hill MH, McDowell IF, Pullin CH, Ashfield-Watt PA, Clark ZE, Whiting JM, Newcombe RG, Lewis MJ, Powers HJ. Moat SJ, et al. Among authors: lewis mj. Eur J Clin Nutr. 2003 Mar;57(3):483-9. doi: 10.1038/sj.ejcn.1601554. Eur J Clin Nutr. 2003. PMID: 12627187 Clinical Trial.
Syndrome X and endothelial dysfunction.
Bellamy MF, Goodfellow J, Tweddel AC, Dunstan FD, Lewis MJ, Henderson AH. Bellamy MF, et al. Among authors: lewis mj. Cardiovasc Res. 1998 Nov;40(2):410-7. doi: 10.1016/s0008-6363(98)00184-9. Cardiovasc Res. 1998. PMID: 9893736 Clinical Trial.
733 results