The influence of premedication with 6-OH-dopamine and long-term administration of thymoanaleptics on development of experimental arterial hypertension

Arch Immunol Ther Exp (Warsz). 1976;24(4):491-5.

Abstract

Administration of 6-OH-DA into the lateral cerebral ventricle did not prevent development of hypertension or influence the effects of administration of tricyclic antidepressant drugs (TA). Injection os 6-OH-DA intraperitoneally prevented development of hypertension, and TA apparently protected against the consequences of administration of 6-OH-DA.

MeSH terms

  • Animals
  • Antidepressive Agents, Tricyclic / pharmacology*
  • Catecholamines / urine
  • Dopamine / administration & dosage
  • Dopamine / pharmacology*
  • Female
  • Hypertension / chemically induced*
  • Injections, Intraperitoneal
  • Injections, Intraventricular
  • Male
  • Rats
  • Time Factors

Substances

  • Antidepressive Agents, Tricyclic
  • Catecholamines
  • Dopamine