Splenic abscess in a patient with type 3 Gaucher's disease receiving enzyme replacement therapy

K Maclean; M J Wilson

doi:10.1016/s0022-3476(99)70425-7

Splenic abscess in a patient with type 3 Gaucher's disease receiving enzyme replacement therapy

J Pediatr. 1999 Feb;134(2):245-7. doi: 10.1016/s0022-3476(99)70425-7.

Authors

K Maclean¹, M J Wilson

Affiliation

¹ Departments of Paediatrics and Clinical Genetics, Royal Alexandra Hospital for Children, Sydney, New South Wales, Australia.

PMID: 9931539
DOI: 10.1016/s0022-3476(99)70425-7

Abstract

We report the rare complication of a splenic abscess in an 11-year-old girl with type 3 Gaucher's disease, massive splenomegaly, and a splenic cyst after commencement of enzyme replacement therapy. This case highlights potential difficulties in establishing the diagnosis of splenic abscess in the presence of pre-existing splenic pathology.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Abscess / complications*
Abscess / diagnosis*
Catheters, Indwelling
Child
Cysts / complications
Diseases in Twins
Female
Gaucher Disease / complications*
Gaucher Disease / drug therapy
Glucosylceramidase / administration & dosage
Glucosylceramidase / therapeutic use
Humans
Splenic Diseases / complications*
Splenic Diseases / diagnosis*
Splenomegaly / complications

Substances

alglucerase
Glucosylceramidase