Neurologic manifestations of AIDS: a review of fifty cases in Santos, São Paulo, Brazil

Sao Paulo Med J. 1998 May-Jun;116(3):1715-20. doi: 10.1590/s1516-31801998000300005.

Abstract

Objective: To review the neurologic manifestations of AIDS in patients who were admitted to Hospital Guilherme Alvaro (HGA) due to any clinical manifestation of the disease.

Design: Case series.

Patients: All HIV+ patients admitted to the Faculty Hospital (HGA) between July 96 and April 97 were included in this review.

Results: From the 117 HIV+ patients admitted to hospitalization due to AIDS-related symptoms, 50 (42.7%) presented neurologic manifestations. The most prevalent of these was neurotoxoplasmosis (68%), but a variety of other neurologic diseases were observed. Only 36% of these 50 patients had neurological signs and symptoms as the main complaint for admission, 12% of the patients had at least complained of some neurologic dysfunction at the time of admission and 10% had no neurologic complaints at all. The remaining 42% (21 patients) only complained of neurologic manifestations of AIDS when specifically asked.

Conclusions: The prevalence of neurologic manifestations of AIDS is very high in patients admitted to hospital. Even in the absence of neurologic-related complaints, these patients have to be carefully questioned and examined in the search for an underlying neurologic complication which may present high morbidity and mortality.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adolescent
  • Adult
  • Brazil
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nervous System Diseases / complications*
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / epidemiology
  • Prevalence