The antifungal drug clotrimazole

Acta Crystallogr C. 1998 Nov 15:54 ( Pt 11):1675-7. doi: 10.1107/s0108270198006386.

Abstract

The structure of the title compound, 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole, C22H17ClN2, has been determined. The molecular conformation showed a weathercock-type structure and the three phenyl rings are almost perpendicular to the imidazole ring. The distances between the centres of the three phenyl rings and the centre of the imidazole ring are in the range 4.52-4.54 A.

MeSH terms

  • Antifungal Agents / chemistry*
  • Clotrimazole / chemistry*
  • Crystallography, X-Ray
  • Molecular Conformation

Substances

  • Antifungal Agents
  • Clotrimazole