The interest of tumors of salivary gland has increased according to the nosology, diagnosis and therapeutic aspects. This study object to appreciate the frequency of this pathology at the ENT Department of the University Hospital Center of Ouagadougou and to report our experience in their diagnostic and therapeutic management. We have collected 48 cases, representing 2% of the department surgery activity and 7% of the tumors operated between 1985 and 1996. This report has concerned 32 parotid tumors (66.7%), 10 submaxillary tumors (20.8%), 6 minor gland tumors (12.5%). This series was composed of 28 women and 20 men with an average age of 41 years. Diagnosis management was based on clinical, radiologic and echographic examination. The correlation between preoperative and histological diagnosis was correct in 88.7% cases. Benign tumors represented 83.3% of the cases with essentially pleomorphic adenomas, and the malignant tumors 16.7% cases. Post operative evolution was simple in 85.4% cases. After 3 years, local recurrence occurred in 4 cases. The prognosis of malignant tumors has been unsatisfactory: the survival rate at 3 years has been 20%.