Abstract
Seven acetophenone derivatives were isolated from the aerial parts of Ophryosporus axilliflorus (Griseb.) Hieron. These compounds were subjected to the carrageenan-induced mouse paw edema test where tremetone (7) showed extremely anti-inflammatory activity. Furthermore, the non-benzofuran acetophenones 5 and 6, showed a significant response.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetophenones / chemistry
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Acetophenones / isolation & purification
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Acetophenones / pharmacology*
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / chemistry
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Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
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Chromatography, High Pressure Liquid
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Female
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Magnetic Resonance Spectroscopy
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Male
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Mice
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Plants, Medicinal / chemistry*
Substances
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Acetophenones
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Anti-Inflammatory Agents, Non-Steroidal