Abstract
Optimal dosage for chemotherapy administered to patients on chronic hemodialysis remains a difficult question. We report the case of a patient with chronic renal failure on hemodialysis for 9 years who was treated for small-cell lung cancer. The chemotherapy protocol combined carboplatin and etoposide at doses adapted to creatinine clearance. Tumor regression was observed after 6 cycles without major intolerance.
Publication types
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Case Reports
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English Abstract
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Review
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Carboplatin / administration & dosage
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Carboplatin / adverse effects
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Carcinoma, Bronchogenic / complications
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Carcinoma, Bronchogenic / drug therapy*
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Carcinoma, Small Cell / complications
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Carcinoma, Small Cell / drug therapy*
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Etoposide / administration & dosage
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Etoposide / adverse effects
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Humans
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Kidney Failure, Chronic / complications
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Kidney Failure, Chronic / drug therapy*
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Lung Neoplasms / complications
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Lung Neoplasms / drug therapy*
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Male
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Middle Aged
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Renal Dialysis*