Central nervous system stem cells in the embryo and adult

J Frisén; C B Johansson; C Lothian; U Lendahl

doi:10.1007/s000180050224

Central nervous system stem cells in the embryo and adult

Cell Mol Life Sci. 1998 Sep;54(9):935-45. doi: 10.1007/s000180050224.

Authors

J Frisén¹, C B Johansson, C Lothian, U Lendahl

Affiliation

¹ Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

PMID: 9791537
DOI: 10.1007/s000180050224

Abstract

The central nervous system is generated from neural stem cells during embryonic development. These cells are multipotent and generate neurons, astrocytes and oligodendrocytes. The last few years it has been found that there are populations of stem cells also in the adult mammalian brain and spinal cord. In this paper, we review the recent development in the field of embryonic and adult neural stem cells.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adult
Animals
Cell Differentiation
Cell Division
Central Nervous System / cytology*
Central Nervous System / embryology*
Central Nervous System / growth & development
Central Nervous System Diseases / therapy
Hippocampus / cytology
Hippocampus / embryology
Hippocampus / growth & development
Humans
Neurons / cytology
Neurons / transplantation
Olfactory Bulb / cytology
Olfactory Bulb / embryology
Olfactory Bulb / growth & development
Signal Transduction
Stem Cell Transplantation
Stem Cells / cytology*