Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil

Farmaco. 1998 Jun 30;53(6):448-9. doi: 10.1016/s0014-827x(98)00043-3.

Abstract

Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid dialcohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for possible cytostatic activity against McCoy cells, using 6-mercaptopurine as a positive control. The samples of sterols and triterpenic dialcohols showed a strong activity.

MeSH terms

  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Cell Division / drug effects
  • Cell Line
  • Humans
  • Iridoid Glucosides
  • Iridoids
  • Olive Oil
  • Phenylethyl Alcohol / analogs & derivatives
  • Phenylethyl Alcohol / pharmacology
  • Plant Oils / chemistry*
  • Pyrans / pharmacology
  • Squalene / pharmacology
  • Sterols / pharmacology
  • Triterpenes / pharmacology

Substances

  • Antineoplastic Agents, Phytogenic
  • Iridoid Glucosides
  • Iridoids
  • Olive Oil
  • Plant Oils
  • Pyrans
  • Sterols
  • Triterpenes
  • 4-hydroxyphenylethanol
  • oleuropein
  • Squalene
  • Phenylethyl Alcohol