Predicting survival in malignant skin melanoma using Bayesian networks automatically induced by genetic algorithms. An empirical comparison between different approaches

Artif Intell Med. 1998 Sep-Oct;14(1-2):215-30. doi: 10.1016/s0933-3657(98)00024-4.

Abstract

In this work we introduce a methodology based on genetic algorithms for the automatic induction of Bayesian networks from a file containing cases and variables related to the problem. The structure is learned by applying three different methods: The Cooper and Herskovits metric for a general Bayesian network, the Markov blanket approach and the relaxed Markov blanket method. The methodologies are applied to the problem of predicting survival of people after 1, 3 and 5 years of being diagnosed as having malignant skin melanoma. The accuracy of the obtained models, measured in terms of the percentage of well-classified subjects, is compared to that obtained by the so-called Naive-Bayes. In the four approaches, the estimation of the model accuracy is obtained from the 10-fold cross-validation method.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Artificial Intelligence
  • Bayes Theorem*
  • Crosses, Genetic
  • Databases as Topic
  • Expert Systems
  • Follow-Up Studies
  • Forecasting
  • Humans
  • Markov Chains
  • Melanoma / diagnosis*
  • Melanoma / genetics
  • Mutation / genetics
  • Neural Networks, Computer*
  • Reproducibility of Results
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / genetics
  • Survival Rate