Abstract
Over three generations, several members of a family suffered from cardiomyopathy exhibiting, primarily, rhythm and conduction disturbances and, eventually, congestive heart failure. Certain serum enzymes (SGOT, SGPT, LDH) were elevated. The clinical examination indicated a progressive deterioration with increasing age of the patients, a more serious course in the male members of the family, and the frequent association of mental retardation.
MeSH terms
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Adolescent
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Adult
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Alanine Transaminase / blood
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Arrhythmias, Cardiac / enzymology
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Arrhythmias, Cardiac / genetics
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Aspartate Aminotransferases / blood
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Cardiomyopathies / enzymology
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Cardiomyopathies / genetics*
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Female
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Heart Failure / enzymology
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Heart Failure / genetics
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Humans
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L-Lactate Dehydrogenase / blood
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Male
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Middle Aged
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Pedigree
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Sex Factors
Substances
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L-Lactate Dehydrogenase
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Aspartate Aminotransferases
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Alanine Transaminase