Abstract
The authors report a case of a 76-year-old man, with not past history of abnormal bleeding, who suffered an acute, recurrent, intestinal haemorrhage from extensive angiodysplasia of the colon. Intestinal bleeding and angiodysplasia were associated with a von Willebrand's disease. Genetic analysis showed a point mutation in arginine 611 of the mature von Willebrand's factor subunit (A1 loop) confirming a von Willebrand's disease type 2.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Angiodysplasia / complications
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Angiodysplasia / diagnosis*
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Colon / blood supply
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Diverticulum, Colon / complications
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Gastrointestinal Hemorrhage / etiology*
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Humans
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Male
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Mutation, Missense
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Pedigree
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Recurrence
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von Willebrand Diseases / blood
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von Willebrand Diseases / classification
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von Willebrand Diseases / complications
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von Willebrand Diseases / diagnosis*
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von Willebrand Diseases / genetics