A phase I clinical trial of lethally irradiated allogeneic pancreatic tumor cells transfected with the GM-CSF gene for the treatment of pancreatic adenocarcinoma

Hum Gene Ther. 1998 Sep 1;9(13):1951-71. doi: 10.1089/hum.1998.9.13-1951.

Authors

E M Jaffee¹, R Abrams, J Cameron, R Donehower, M Duerr, J Gossett, T F Greten, L Grochow, R Hruban, S Kern, K D Lillemoe, S O'Reilly, D Pardoll, H A Pitt, P Sauter, C Weber, C Yeo

Affiliation

¹ Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. ejaffee@welchlink.welch.jhu.edu

PMID: 9741433
DOI: 10.1089/hum.1998.9.13-1951

No abstract available

Publication types

Clinical Trial
Clinical Trial, Phase I
Randomized Controlled Trial

MeSH terms

Adenocarcinoma / genetics
Adenocarcinoma / therapy*
Cancer Vaccines / therapeutic use*
Clinical Protocols
Genetic Therapy / methods*
Granulocyte-Macrophage Colony-Stimulating Factor* / genetics
Humans
Pancreatic Neoplasms / genetics
Pancreatic Neoplasms / therapy*
Patient Selection
Vaccination

Substances

Cancer Vaccines
Granulocyte-Macrophage Colony-Stimulating Factor