A fuzzy logic based control system to monitor and control the electrical and chemical responses of nerve fibers has been designed and simulated. Fuzzy logic provides powerful reasoning mechanisms for combining information from multiple fuzzy sets.... The rule base has been developed based on the difference between the measured value and the desired value. The potential difference across each nerve fiber and the current through it has been monitored and controlled by a feedback control signal. The controller has been tested and simulated using sinusoidal and square wave forms with different frequency. The desired value was reached very rapidly. The system is capable of monitoring and controlling four nerve fibers simultaneously and allow the researcher to select different modes of operations.