Verapamil prevents cyclosporine-induced hypertension by modulating endothelin A receptor expression in rat kidney membranes

Transplant Proc. 1998 Aug;30(5):2028-9. doi: 10.1016/s0041-1345(98)00520-x.
No abstract available

MeSH terms

  • Animals
  • Blood Pressure / drug effects
  • Cell Membrane / metabolism
  • Cyclosporine / toxicity*
  • Endothelin-1 / metabolism
  • Gene Expression Regulation / drug effects
  • Hypertension / chemically induced*
  • Hypertension / prevention & control*
  • Iodine Radioisotopes
  • Kidney / drug effects*
  • Kidney / metabolism
  • Male
  • Radioligand Assay
  • Rats
  • Rats, Wistar
  • Receptor, Endothelin A
  • Receptors, Endothelin / biosynthesis*
  • Receptors, Endothelin / genetics
  • Verapamil / pharmacology*

Substances

  • Endothelin-1
  • Iodine Radioisotopes
  • Receptor, Endothelin A
  • Receptors, Endothelin
  • Cyclosporine
  • Verapamil