Role of P-glycoprotein in chronic cyclosporine nephrotoxicity and its relationship to intrarenal angiotensin II deposits

Transplant Proc. 1998 Aug;30(5):2014-6. doi: 10.1016/s0041-1345(98)00515-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / biosynthesis*
  • Angiotensin II / metabolism*
  • Animals
  • Creatinine / blood
  • Cyclosporine / toxicity*
  • Fibrosis
  • Immunosuppressive Agents / toxicity
  • Kidney / drug effects*
  • Kidney / metabolism
  • Kidney / pathology
  • Kidney Cortex / drug effects
  • Kidney Cortex / metabolism
  • Kidney Cortex / pathology
  • Kidney Tubules / drug effects
  • Kidney Tubules / metabolism
  • Kidney Tubules / pathology
  • Male
  • Rats
  • Rats, Sprague-Dawley

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Immunosuppressive Agents
  • Angiotensin II
  • Cyclosporine
  • Creatinine