Abstract
We describe a case of severe anticholinergic intoxication following the topical instillation of tropicamide-containing eyedrops. Tropicamide is a short-acting atropine-like derivative and has been regarded as an effective and safe mydriatic. Half an hour after routine fundoscopy, a 62-year-old man experienced two generalized seizures with respiratory arrest and required intubation and mechanical ventilation. The patient was treated with physostigmine and made a full recovery.
MeSH terms
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Antidotes / therapeutic use
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Humans
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Instillation, Drug
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Male
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Middle Aged
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Muscarinic Antagonists / poisoning*
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Mydriatics / poisoning*
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Ophthalmic Solutions
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Ophthalmoscopy*
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Physostigmine / therapeutic use
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Respiration, Artificial
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Respiratory Insufficiency / chemically induced*
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Respiratory Insufficiency / therapy
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Seizures / chemically induced*
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Seizures / therapy
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Tropicamide / poisoning*
Substances
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Antidotes
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Muscarinic Antagonists
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Mydriatics
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Ophthalmic Solutions
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Physostigmine
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Tropicamide