Antidiarrhoeal activity of Waltheria americana, Commelina coelestis and Alternanthera repens

J Ethnopharmacol. 1998 May;61(1):41-7. doi: 10.1016/s0378-8741(98)00014-2.

Abstract

The antidiarrhoeal activity of the hexane, chloroform, methanol and aqueous extracts of Waltheria americana, Commelina coelestis and Alternathera repens, was tested on mice with diarrhoea induced by castor oil and MgSO4. The methanol extract of C. coelestis and A. repens and aqueous extract of A. repens, presented antidiarrhoeal effect, monitored by number of liquid feces defecated and intestinal transit of a suspension of graphite with castor oil in Wistar rats.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Animals
  • Antidiarrheals / administration & dosage
  • Antidiarrheals / therapeutic use*
  • Castor Oil
  • Chloroform
  • Diarrhea / chemically induced
  • Diarrhea / drug therapy*
  • Gastrointestinal Transit / drug effects
  • Graphite
  • Hexanes
  • Magnesium Sulfate
  • Male
  • Methanol
  • Mexico
  • Plant Extracts / administration & dosage
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*
  • Rats
  • Rats, Wistar

Substances

  • Antidiarrheals
  • Hexanes
  • Plant Extracts
  • n-hexane
  • Magnesium Sulfate
  • Graphite
  • Chloroform
  • Castor Oil
  • Methanol