A retrospective study was undertaken on the prevalence and etiology of unilateral sensorineural hearing impairment (> 25 dB at 0.5-4 kHz, including mixed hearing impairments with bone conduction thresholds > or = 25 dB) among children born between 1972 and 1986 in a province of eastern Finland. Only patients who had been diagnosed before the age of 10 years were included. A total of 84 children with such an unilateral hearing loss were identified, with prevalence of 1.7 per 1000 live births. A significant decline from the prevalence of 2.2 per 1000 in the 1970s to the prevalence of 1.2 per 1000 in the 1980s was observed, which was mainly due to the disappearance of hearing losses caused by mumps and measles in the 1980s and the decrease in cases attributed to otitis media. In agreement with some previous studies, a considerable male predominance was present. Thirty-five percent of the hearing losses were profound (> 95 dB) and 15% were severe (71-95 dB). Etiology of the hearing impairment was estimated as genetic in 2%, congenital non-genetic in 12%, delayed-onset non-genetic in 35% and remained unknown in 51%.