Based on Merlin's concept of integrative individuality, the following individual levels in types A and type B behavior were studied: psychological (character, locus of subjective control), psychophysiological (temperament, emotionality, psychomotor activity) and neurophysiological (behavioral, electrocortical, and vegetative activations). The distinction in the character and temperament parameters between both of behavior patterns was prevalent. Several accentuated profiles of type A persons behavior were established according to the individual combination of the character and temperament indices. The profile that combined emotionality and activity ("passionate") was confirmed as a behavioral risk factor in the group of the patients with ischemic heart disease. A new test for differential evaluation of psychophysiological profiles of type A behavior was developed and standardized. In the clinical part of the investigation it was the most effective in revealing the psychological risk factor in patients with ischemic heart disease.