Early carotid endarterectomy after non-disabling ischaemic stroke: adequate therapeutical option in selected patients

Eur J Vasc Endovasc Surg. 1998 May;15(5):423-8. doi: 10.1016/s1078-5884(98)80204-9.

Abstract

Objective: To evaluate neurological outcome and long-term results of early carotid endarterectomy (CEA) after non-disabling stroke.

Materials: Retrospective study between 1980 and 1995 of 56 patients undergoing CEA within 4 weeks of a transient (n = 15) or a permanent non-disabling (n = 41) ischaemic stroke.

Methods: Analyses of preoperative cerebral CT imaging, neurological outcome (mod. Rankin-scale) and long-term results (life-table analyses according to Kaplan-Meier).

Results: Incidence of early CEA increased from 1.7% (27 out of 1636) in the period 1980-1993 to 7.8% (29 out of 374) between 1994 and 1995. CEA was indicated after a neurological plateau phase was established (median interval 14 days). Fifty-seven per cent of the CEA patients had a minor ischaemic infarction (area < 2 cm), 18% showed a large territorial ischaemic infarction (area 2-5 cm) in cerebral CT imaging. Two patients deteriorated postoperatively (minor stroke rate 4%) but no major stroke or death occurred. Life-table probability of stroke-free survival (mean follow-up 42.7 months) was 94%, 90% and 84%, respectively, after 1, 2 and 5 years. Kaplan-Meier survival rates were 96%, 91% and 86% after 1, 2 and 5 years.

Conclusions: Early CEA after non-disabling stroke is a safe procedure in selected patients.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain / diagnostic imaging
  • Brain Ischemia / diagnostic imaging
  • Brain Ischemia / surgery
  • Cerebral Infarction / etiology
  • Cerebrovascular Disorders / diagnostic imaging
  • Cerebrovascular Disorders / surgery
  • Disease-Free Survival
  • Endarterectomy, Carotid*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Ischemic Attack, Transient / diagnostic imaging
  • Ischemic Attack, Transient / surgery*
  • Life Tables
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Neurologic Examination
  • Patient Selection
  • Retrospective Studies
  • Safety
  • Survival Rate
  • Tomography, X-Ray Computed
  • Treatment Outcome