MRI of hyperpolarized 3He gas in human paranasal sinuses

Magn Reson Med. 1998 Jun;39(6):865-8. doi: 10.1002/mrm.1910390603.

Abstract

In this study, MRI of hyperpolarized 3He gas in human paranasal sinuses is presented. Helium images were obtained at 1.5 T, using a surface coil and a 2D, fast gradient-echo sequence with a nominal constant flip angle of 12 degrees. Coronal images of 20-mm thick slices were generated and compared with proton images of the corresponding sections. The images enable visualization of the paranasal sinuses and the nasal cavity, suggesting a potential use of this method not only in identifying the anatomical configuration of these pneumatic spaces, but also in assessing sinus ventilation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Contrast Media*
  • Helium*
  • Humans
  • Image Processing, Computer-Assisted / instrumentation
  • Isotopes
  • Magnetic Resonance Imaging* / instrumentation
  • Male
  • Nasal Cavity / anatomy & histology
  • Paranasal Sinuses / anatomy & histology*
  • Pulmonary Ventilation / physiology
  • Reference Values
  • Sensitivity and Specificity

Substances

  • Contrast Media
  • Isotopes
  • Helium