Interindividual variability in Swiss male mice: relationship between social factors, aggression, and anxiety

Physiol Behav. 1998 Mar;63(5):821-7. doi: 10.1016/s0031-9384(97)00544-1.

Abstract

In the present study we carried out a series of experiments in Swiss albino male mice to investigate a) the effects of previous social experience on the levels of anxiety in the elevated plus-maze (EPM) and b) whether the response of males in the EPM differs in relation to the different social status. In Experiment 1 we tested in the EPM male mice that received different social experience. Results showed that individually housing generally increased measures of anxiety in the EPM compared with the group-housing condition. Moreover, aggressive males, screened during dyadic encounters in a neutral cage, displayed the highest levels of anxiety relative to the other experimental conditions. In Experiment 2 male mice remained group-housed and were observed to record their social status. Results showed that those animals rated as socially dominant displayed a higher level of EPM anxiety relative to subordinates. From an ethological perspective our findings may be interpreted in terms of coping strategies, with aggressive/dominant animals typified by higher levels of risk assessment and open-arm avoidance than defensive/subordinate animals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aggression / psychology*
  • Animals
  • Anxiety / psychology*
  • Arousal
  • Avoidance Learning
  • Dominance-Subordination*
  • Hierarchy, Social
  • Individuality
  • Male
  • Maze Learning*
  • Mice
  • Motor Activity
  • Social Environment*