A study on the relation between proton pump inhibitor and gastric giardiasis

J Egypt Soc Parasitol. 1998 Apr;28(1):149-57.

Abstract

Thirty patients treated with proton pump inhibitor and still having symptoms related to gastritis or peptic ulcers were subjected to upper gastrointestinal endoscopy and gastric biopsy for detection of giardiasis in these cases. Results showed presence of 3 (10%) cases of gastric giardiasis, intestinal metaplasia and presence of H. pylori in these cases. It is concluded that there may be a relation between the presence of gastric giardiasis and the intake of proton pump inhibitor. The endoscopists have to search for gastric giardiasis especially in the presence of H. pylori and/or intestinal metaplasia.

MeSH terms

  • Adult
  • Animals
  • Anti-Ulcer Agents / adverse effects*
  • Anti-Ulcer Agents / therapeutic use
  • Female
  • Gastric Mucosa / microbiology
  • Gastric Mucosa / parasitology
  • Gastritis / drug therapy
  • Gastritis / microbiology
  • Gastritis / parasitology
  • Giardia lamblia / isolation & purification
  • Giardiasis / diagnosis
  • Giardiasis / etiology*
  • Giardiasis / parasitology
  • Helicobacter pylori / isolation & purification
  • Humans
  • Male
  • Middle Aged
  • Omeprazole / adverse effects*
  • Omeprazole / therapeutic use
  • Peptic Ulcer / drug therapy
  • Proton Pump Inhibitors*
  • Stomach Diseases / diagnosis
  • Stomach Diseases / etiology*
  • Stomach Diseases / parasitology

Substances

  • Anti-Ulcer Agents
  • Proton Pump Inhibitors
  • Omeprazole