Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9

Vet Immunol Immunopathol. 1998 Jan 30;60(3-4):343-9. doi: 10.1016/s0165-2427(97)00110-4.

Abstract

Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No. 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / metabolism*
  • Antigens, Differentiation, Myelomonocytic / analysis*
  • Kinetics
  • Macrophages / immunology
  • Macrophages, Alveolar / immunology
  • Monocytes / immunology
  • Precipitin Tests
  • Swine / immunology*
  • Swine, Miniature
  • T-Lymphocyte Subsets / immunology

Substances

  • Antibodies, Monoclonal
  • Antigens, Differentiation, Myelomonocytic