Isopoly-L-ornithine derivative as nucleic acid model

Nucleic Acids Symp Ser. 1997:(37):25-6.

Abstract

Isopoly-L-ornithine derivatives of thymine, and thymidine were found to hardly interact with poly A. Conformational studies of the oligomers with CD and NMR revealed that stable intramolecular hydrogen bonding was formed between the thymine base and the ornithine unit.

MeSH terms

  • DNA / chemistry
  • Hydrogen Bonding
  • Isomerism
  • Models, Molecular
  • Models, Structural
  • Nucleic Acid Conformation*
  • Peptides / chemistry*
  • Poly A / chemistry*
  • Protein Conformation*
  • RNA / chemistry
  • Thymidine*
  • Thymine*

Substances

  • Peptides
  • Poly A
  • polyornithine
  • RNA
  • DNA
  • Thymine
  • Thymidine